1276056-81-5

Basic information

• Product Name: 2-a]pyrazine-6-carbonitrile
• Synonyms: 2-a]pyrazine-6-carbonitrile
• CAS NO: 1276056-81-5
• Molecular Formula: C7H4N4
• Molecular Weight: 144.13346
• Mol File: 1276056-81-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-a]pyrazine-6-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-a]pyrazine-6-carbonitrile(1276056-81-5)
• EPA Substance Registry System: 2-a]pyrazine-6-carbonitrile(1276056-81-5)

Safety Data

• Hazardous Substances Data: 1276056-81-5(Hazardous Substances Data)

Usage

General Description

2-Aminopyrazine-6-carbonitrile is a chemical compound with the molecular formula C6H3N3. It is a heterocyclic organic compound that contains a pyrazine ring and a cyano group. 2-a]pyrazine-6-carbonitrile is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as an intermediate in the manufacture of dyes and pigments. 2-Aminopyrazine-6-carbonitrile is known for its versatility and its ability to participate in a wide range of chemical reactions, making it an important precursor in the production of various organic compounds. It is important to handle this chemical with care, as it may have hazardous properties if not used properly.

Upstream product

• 557-21-1 zinc(II) cyanide 
• 912773-24-1 6-bromo-imidazo[1,2-a]pyrazine 
• 113305-94-5 2-amino-5-cyanopyrazine 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 107-20-0 2-chloroethanal 

Downstream Products

• 1362159-53-2 N-{[4-(benzenesulfonyl)phenyl]methyl}imidazo[1,2-a]pyrazine-6-carboxamide 

Relevant articles and documents

IMIDAZO-PYRAZINYL DERIVATIVES USEFUL AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS

A compound of Formula I or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate ("cGMP") and are generally suitable for the therapy and prophylaxis of diseases which are associated w

Discovery of (S)-1-(1-(Imidazo[1,2- a ]pyridin-6-yl)ethyl)-6-(1-methyl-1 H -pyrazol-4-yl)-1 H -[1,2,3]triazolo[4,5- b ]pyrazine (Volitinib) as a Highly Potent and Selective Mesenchymal-Epithelial Transition Factor (c-Met) Inhibitor in Clinical Development for Treatment of Cancer

HGF/c-Met signaling has been implicated in human cancers. Herein we describe the invention of a series of novel triazolopyrazine c-Met inhibitors. The structure-activity relationship of these compounds was investigated, leading to the identification of compound 28, which demonstrated favorable pharmacokinetic properties in mice and good antitumor activities in the human glioma xenograft model in athymic nude mice.

CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR

Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.