1276076-00-6

Basic information

• Product Name: Methyl 2-(1H-pyrazol-4-yl)acetate
• Synonyms: Methyl 2-(1H-pyrazol-4-yl)acetate;(1H-Pyrazol-4-yl)-acetic acid methyl ester
• CAS NO: 1276076-00-6
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.13992
• Mol File: 1276076-00-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 278.5±15.0 °C(Predicted)
• Appearance: /
• Density: 1.231±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.78±0.50(Predicted)
• CAS DataBase Reference: Methyl 2-(1H-pyrazol-4-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(1H-pyrazol-4-yl)acetate(1276076-00-6)
• EPA Substance Registry System: Methyl 2-(1H-pyrazol-4-yl)acetate(1276076-00-6)

Safety Data

• Hazardous Substances Data: 1276076-00-6(Hazardous Substances Data)

Upstream product

• 934172-55-1 (1H-pyrazol-4-yl)-acetic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 1394373-94-4 2-[1-[6-[4-[2-[[(3R,3aR,6R,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl]oxy]-6-chloro-1-(2-trimethylsilylethoxymethyl)imidazo[4,5-b]pyridin-5-yl]phenyl]-3-pyridyl]pyrazol-4-yl]acetic acid 
• 1394374-02-7 2-[1-[5-[4-[2-[[(3R,3aR,6R,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl]oxy]-6-chloro-1-(2-trimethylsilylethoxymethyl)imidazo[4,5-b]pyridin-5-yl]phenyl]-2-pyridyl]pyrazol-4-yl]acetic acid 
• 1394372-57-6 (3R,3aR,6R,6aR)-6-[[6-chloro-5-[4-[5-[4-(2-hydroxy-2-methyl-propyl)pyrazol-1-yl]-2-pyridyl]phenyl]-1H-imidazo[4,5-b]pyridin-2-yl]oxy]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-ol 
• 1394373-77-3 1-(1-(4-bromophenyl)-1H-pyrazol-4-yl)-2-methylpropan-2-ol 
• 1394373-96-6 methyl 2-[1-[6-[4-[2-[[(3R,3aR,6R,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl]oxy]-6-chloro-1-(2-trimethylsilylethoxymethyl)imidazo[4,5-b]pyridin-5-yl]phenyl]-3-pyridyl]pyrazol-4-yl]acetate 
• 1394373-98-8 (3R,3aR,6R,6aR)-6-[6-chloro-5-[4-[5-[4-(2-hydroxy-2-methyl-propyl)pyrazol-1-yl]-2-pyridyl]phenyl]-1-(2-trimethylsilylethoxymethyl)imidazo[4,5-b]pyridin-2-yl]oxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-ol 
• 1394374-04-9 methyl 2-[1-[5-[4-[2-[[(3R,3aR,6R,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl]oxy]-6-chloro-1-(2-trimethylsilylethoxymethyl)imidazo[4,5-b]pyridin-5-yl]phenyl]-2-pyridyl]pyrazol-4-yl]acetate 
• 1394374-06-1 2-[1-[5-[4-[2-[[(3R,3aR,6R,6aR)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl]oxy]-6-chloro-1H-imidazo[4,5-b]pyridin-5-yl]phenyl]-2-pyridyl]pyrazol-4-yl]acetic acid 

Relevant articles and documents

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Novel compounds of structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.