1276111-01-3Relevant academic research and scientific papers
Optimization of Catalyst Structure for Asymmetric Propargylation of Aldehydes with Allenyltrichlorosilane
Vaganov, Vladimir Yu.,Fukazawa, Yasuaki,Kondratyev, Nikolay S.,Shipilovskikh, Sergei A.,Wheeler, Steven E.,Rubtsov, Aleksandr E.,Malkov, Andrei V.
, p. 5467 - 5474 (2020)
The design of catalysts for asymmetric propargylations remains a challenging task, with only a handful of methods providing access to enantioenriched homopropargylic alcohols. In this work, guided by previously reported computational predictions, a set of
Helical chiral 2,2′-bipyridine N-monoxides as catalysts in the enantioselective propargylation of aldehydes with allenyltrichlorosilane
Chen, Jinshui,Captain, Burjor,Takenaka, Norito
supporting information; experimental part, p. 1654 - 1657 (2011/05/15)
A highly enantioselective synthesis of homopropargylic alcohols is achieved by using the new helical chiral 2,2′-bipyridine N-monoxide catalyst and allenyltrichlorosilane. This method can be further extended to the enantio- and regioselective propargylati
