1276113-20-2Relevant academic research and scientific papers
A domino process for benzyne preparation: Dual activation of o-(trimethylsilyl)phenols by nonafluorobutanesulfonyl fluoride
Ikawa, Takashi,Nishiyama, Tsuyoshi,Nosaki, Toshifumi,Takagi, Akira,Akai, Shuji
supporting information; experimental part, p. 1730 - 1733 (2011/06/16)
Benzynes were generated from o-(trimethylsilyl)phenols using nonafluorobutanesulfonyl fluoride (NfF) by a domino process, i.e., the nonaflation of the phenolic hydroxyl group of o-(trimethylsilyl)phenols by NfF followed by the attack of the produced fluoride ion on the trimethylsilyl group. The generated benzyne immediately underwent various reactions to give polysubstituted benzenes.
