127612-66-2

Upstream product

• 118964-34-4 (-)-Fisetinidol-(4α,8)-(+)-catechin 4-O(E)-methyl ether 
• 967-27-1 (+)-mollisacacidin 

Downstream Products

• 102258-24-2 (2R,3S,4S,6R,7S,8S,10R,11S)-2,6,10-Tris-(3,4-dihydroxy-phenyl)-4,8-bis-(2,4-dihydroxy-phenyl)-3,4,7,8,11,12-hexahydro-2H,6H,10H-dipyrano[2,3-f;2',3'-h]chromene-3,7,11-triol 
• 127612-67-3 (2R,3S,4S,8R,9S)-2,8-Bis-(3,4-dihydroxy-phenyl)-4-(2,4-dihydroxy-phenyl)-6-[(2R,3S,4S)-2-(3,4-dihydroxy-phenyl)-3,7-dihydroxy-chroman-4-yl]-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromene-3,5,9-triol 
• 105805-45-6 (2R,3S,8R,9S,10S)-2,8-Bis-(3,4-dihydroxy-phenyl)-10-(2,4-dihydroxy-phenyl)-6-[(2R,3S,4S)-2-(3,4-dihydroxy-phenyl)-3,7-dihydroxy-chroman-4-yl]-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromene-3,5,9-triol 

Relevant academic research and scientific papers

Oligomeric Flavanoids. Part 11. Structure and Synthesis of the First Phlobatannins Related to (4α,6:4α,8)-Bis-fisetinidol-(+)-catechin Profisetinidin Triflavanoids

Several members of the unique class of natural phlobatannins, representing the products of stereospecific pyran rearrangement of 2,3-trans-3,4-trans-flavan-3-ol units present in, e.g., (4α,6:4α,8)-bis-(-)-fisetinidol-(+)-catechin triflavanoid profisetinidins, have been characterized.These include the functionalized 6,7-trans-7,8-cis-10,11-trans-11,12-cis-hexahydrodipyranochromene (3) and the 10-flavanyl-6,7-trans-7,8-cis-tetrahydropyranochromene 'isomerisation-intermediates' (6), (15), and (17).The proposed structures of compounds (3) and (6) were confirmed by synthesis via base-catalysed conversion of the 3-O(E)-methyl ether (1) of its apparent biogenetic precursor, and the relative nucleophilicity of the A- and D-ring in the 'dimeric' tetrahydropyranochromene (14) assessed by condensation with the flavan-3,4-diol, (+)-mollisacacidin.