1276121-67-5Relevant academic research and scientific papers
Co(III) catalysed asymmetric ring-opening of epichlorohydrin by salicylaldehyde derivatives: Reversal of enantioselectivity and rate acceleration on addition of AlCl3
Karadeniz, Leman,Koz, Gamze,Aydin, Kadriye,Astley, Stephen T.
experimental part, p. 711 - 718 (2010/12/25)
Using asymmetric Cobalt(III) salen catalysts, the ring-opening of epichlorohydrin by 2, 3-dihydroxybenzal- dehyde and 2, 4- dihydroxybenzaldehyde was found to occur at the phenolic groups most distant from the aldehydic group. Switching catalysts afforded a reversal in enantioselectivity. For 2, 3-dihydroxybenzaldehyde and salicylaldehyde, addition of AlCl3 to the reaction mixture led to an increase in reaction rate without any decrease in product enantiopurity. TUeBITAK.
