127630-48-2

Basic information

• Product Name: 6-(1-{(E)-3-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-2-hydroxy-propoxyimino}-ethyl)-4H-benzo[1,4]thiazin-3-one
• CAS NO: 127630-48-2
• Molecular Weight: 459.566
• Mol File: 127630-48-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-(1-{(E)-3-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-2-hydroxy-propoxyimino}-ethyl)-4H-benzo[1,4]thiazin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(1-{(E)-3-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-2-hydroxy-propoxyimino}-ethyl)-4H-benzo[1,4]thiazin-3-one(127630-48-2)
• EPA Substance Registry System: 6-(1-{(E)-3-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-2-hydroxy-propoxyimino}-ethyl)-4H-benzo[1,4]thiazin-3-one(127630-48-2)

Safety Data

• Hazardous Substances Data: 127630-48-2(Hazardous Substances Data)

Upstream product

• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 127630-40-4 6-<1-<(2,3-epoxy)-propoxy>-iminoethyl>-3,4-dihydro-3-oxo-2H-1,4-benzothiazine 
• 91119-38-9 6-Acetyl-2H-1,4-benzothiazine-3(4H)-one 
• 127630-36-8 3,4-dihydro-3-oxo-2H-1,4-benzothiazin-6-acetoxime 

Relevant articles and documents

Synthesis and β-adrenergic blocking activity of 1,4-benzothiazine oxime ethers

Synthesis of 6-, 7-, 8-acetimidoyloxypropanolamines of 3,4-dihydro-3-oxo-2H-1,4-benzothiazine and 8-iminoxypropanolamines of 3,4,5,6,7,8-hexahydro-3-oxo-2H-1,4-benzothiazine are reported.All of the synthesized compounds were tested in vitro for their ability to displace dihydroalprenolol from turkey erythrocyte membranes and in vivo for their β-adrenoceptor blocking activity by the inhibition of isoprenaline-induced tachycardia and compared with the corresponding oxypropanolamines which we had previously described as β-blockers. - oxime ethers/β-blockers/1,4-benzothiazine