127634-16-6Relevant articles and documents
SYNTHESIS OF THE ENANTIOMERS OF FELODIPINE AND DETERMINATION OF THEIR ABSOLUTE CONFIGURATION
Lamm, Bo,Simonsson, Roger,Sundell, Staffan
, p. 6423 - 6426 (2007/10/02)
The pure enantiomers of felodipine, 1, have been synthesized by chromatographic separation of diastereomeric esters with (R)-1-(p-toluenesulfonyl)-3-trityloxypropan-2-ol, 3, as an easily removable chiral auxiliary.Absolute configurations have been deduced