127643-61-2

Upstream product

• 79-77-6 (E)-β-ionone 
• 14398-35-7 (3E)-4-(2,6,6-trimethylcyclohexa-1,3-dien-1-yl)but-3-en-2-one 
• 116296-75-4 (rac)-(E)-4-(4-hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one 
• 142739-15-9 2-Methyl-2-[(E)-2-(2,6,6-trimethyl-cyclohexa-1,3-dienyl)-vinyl]-[1,3]dioxolane 
• 142739-16-0 3-hydroxy-β-ionone 

Relevant academic research and scientific papers

Synthesis of (±)-E-4-(1,2,4-trihydroxy-2,6,6-trimethylcyclohexyl)-but-3-en-2-one: A novel degraded carotenoid isolated from New Zealand thyme (Thymus vulgaris) honey

A racemic synthesis of the title compound is described starting from β-ionone. The key steps involve selective hydroboration of a triene, followed by molybdenum mediated epoxidation of the resulting homoallylic alcohol with subsequent ring opening of the epoxide to give the title compound.