127643-98-5Relevant academic research and scientific papers
Asymmetric synthesis of nonproteinogenic amino acids with l-amino acid transaminase: synthesis of (2S)-2-amino-4-oxo-4-phenylbutyric and (3E,2S)-2-amino-4-phenylbutenoic acids
Fadnavis, Nitin W.,Seo, Su-Hyun,Seo, Joo-Hyun,Kim, Byung-Gee
, p. 2199 - 2202 (2006)
2,4-Dioxo-4-phenylbutyric acid and 2-oxo-4-phenylbut-3-enoic acid are converted to the corresponding (S)-2-amino acids by recombinant Escherichia coli whole cells over-expressing aromatic transaminase from Enterobacter sp. BK2K-1 (AroATEs) in high yields (68-78%) and high enantiomeric purity (>99%) using l-aspartic acid as an amino donor.
Non-Proteinogenic Amino Acid Synthesis: Synthesis of β,γ-Unsaturated α-Amino Acids from Aspartic Acid
Baldwin, Jack E.,Moloney, Mark G.,North, Michael
, p. 6319 - 6330 (2007/10/02)
A general, stereospecific, synthesis of β,γ-unsaturated α-amino acids using the β-anion derived from aspartic acid is described.Keywords: aspartic acid; unsaturated acids
