127657-29-8 Usage
Uses
Different sources of media describe the Uses of 127657-29-8 differently. You can refer to the following data:
1. 3-Carbethoxythiazolidine-4-Carboxylic Acid is an intermediate in the synthesis of N-Carbethoxy-4-thiazolidinecarboxylic acid useful for treatment of chronic and acute affections of the respiratory system.
2. 3,4-Thiazolidinedicarboxylic Acid 3-Ethyl Ester is an intermediate in the synthesis of N-Carbethoxy-4-thiazolidinecarboxylic acid useful for treatment of chronic and acute affections of the respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 127657-29-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,6,5 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 127657-29:
(8*1)+(7*2)+(6*7)+(5*6)+(4*5)+(3*7)+(2*2)+(1*9)=148
148 % 10 = 8
So 127657-29-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H11NO4S/c1-2-12-7(11)8-4-13-3-5(8)6(9)10/h5H,2-4H2,1H3,(H,9,10)
127657-29-8Relevant articles and documents
The use of Curtius rearrangement in the synthesis of 4- aminothiazolidines
Braibante, Mara E.F.,Braibante, Hugo S.,Costenaro, Edson R.
, p. 943 - 946 (2007/10/03)
The amine group of the L-cysteine was protected as (4R)-1,3- thiazolidines-4-carboxylic acids 2a-b and was used for the synthesis of functionalized 1,3-diamines by the way of Curtius reaction. An optimization of this methodology was made using the acylation in situ of the amine group of the thiazolidines and the activation of the carboxylic acid, after Curtius rearrangement yielded the ureas 7a,b and 8a and amine derivatives 6a,b. The Curtius reaction occurred without racemization, preserving the chemical and pharmacological importance of these products.
