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1276666-13-7

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1276666-13-7 Usage

General Description

5-Chloro-2-(hexahydro-5-methyl-1H-1,4-diazepin-1-yl)benzoxazole, also known as Vabicaserin, is a chemical compound with a complex molecular structure. It is a selective 5-HT2C receptor agonist and has been studied for its potential use in the treatment of various psychiatric and neurological disorders, particularly schizophrenia and bipolar disorder. The compound has shown promising results in preclinical and clinical trials, with potential for therapeutic applications in modulating serotonin receptors in the central nervous system. Its unique chemical structure and pharmacological properties make it an intriguing candidate for further research and development in the field of neuropsychopharmacology.

Check Digit Verification of cas no

The CAS Registry Mumber 1276666-13-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,6,6,6 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1276666-13:
(9*1)+(8*2)+(7*7)+(6*6)+(5*6)+(4*6)+(3*6)+(2*1)+(1*3)=187
187 % 10 = 7
So 1276666-13-7 is a valid CAS Registry Number.

1276666-13-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Chloro-2-(5-methyl-1,4-diazepan-1-yl)-1,3-benzoxazole

1.2 Other means of identification

Product number -
Other names 5-CHLORO-2-(5-METHYL-1,4-DIAZEPAN-1-YL)BENZO[D]OXAZOLE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1276666-13-7 SDS

1276666-13-7Relevant articles and documents

PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT

-

, (2016/07/05)

A novel processes for the preparation of suvorexant (formula I), its related compounds and its intermediates that are simple, economical and commercially viable. (I)

The first large-scale synthesis of MK-4305: A dual orexin receptor antagonist for the treatment of sleep disorder

Baxter, Carl A.,Cleator, Ed,Brands, Karel M. J.,Edwards, John S.,Reamer, Robert A.,Sheen, Faye J.,Stewart, Gavin W.,Strotman, Neil A.,Wallace, Debra J.

, p. 367 - 375 (2012/05/19)

A new synthetic route to drug candidate 1, a potent and selective dual orexin antagonist for the treatment of sleep disorders, has been developed. The key acyclic precursor 10 was prepared in a one-step process in 75% isolated yield from commercially available starting materials using novel chemistry to synthesize 2-substituted benzoxazoles. A reductive amination was followed by a classical resolution to afford chiral diazepane (R)-11. Finally, coupling of (R)-11 with acid 5 furnished the desired drug candidate 1.

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