1276688-05-1

Basic information

• Product Name: (S)-1-acetyl-2-((S)-1-(3-bromophenyl)-2-nitroethyl)indolin-3-one
• CAS NO: 1276688-05-1
• Molecular Weight: 403.232
• Mol File: 1276688-05-1.mol

Chemical Properties

• CAS DataBase Reference: (S)-1-acetyl-2-((S)-1-(3-bromophenyl)-2-nitroethyl)indolin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-acetyl-2-((S)-1-(3-bromophenyl)-2-nitroethyl)indolin-3-one(1276688-05-1)
• EPA Substance Registry System: (S)-1-acetyl-2-((S)-1-(3-bromophenyl)-2-nitroethyl)indolin-3-one(1276688-05-1)

Safety Data

• Hazardous Substances Data: 1276688-05-1(Hazardous Substances Data)

Upstream product

• 16800-68-3 1-acetyl-2,3-dihydro-1H-indol-3-one 
• 115665-95-7 3-bromo-β-nitro-styrene 

Relevant articles and documents

Asymmetric michael addition of 1-acetylindolin-3-ones to β-nitrostyrenes catalyzed by bifunctional thioureas: A simple access to 2-functionalized indoles

The first asymmetric Michael addition of 1-acetylindolin-3-ones to β-nitrostyrenes has been developed. 2-Substituted indolin-3-one derivatives were obtained with excellent yields (up to 99%) and good stereoselectivities (up to 28:1 dr and 92% ee), which could be transformed into 2-functionalized indoles easily without racemization. This achievement might further contribute to the chemistry and pharmacology of indole-related compounds.