127680-89-1 Usage
General Description
2-PIPERIDIN-1-YLISONICOTINONITRILE, also known as PIPERIDINEISONICOTINONITRILE, is a chemical compound with the molecular formula C11H14N4. It is a nitrile derivative that contains a piperidine ring and a pyridine ring. 2-PIPERIDIN-1-YLISONICOTINONITRILE is commonly used as a building block in organic synthesis and pharmaceutical research. It has been reported to exhibit anti-cancer and anti-inflammatory properties, and its derivatives have shown potential as antitumor agents. Additionally, it has been studied for its potential use as a precursor in the synthesis of various pharmaceuticals and other organic compounds. Due to its unique structure and potential biological activities, 2-PIPERIDIN-1-YLISONICOTINONITRILE is of interest to researchers in the fields of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 127680-89-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,6,8 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 127680-89:
(8*1)+(7*2)+(6*7)+(5*6)+(4*8)+(3*0)+(2*8)+(1*9)=151
151 % 10 = 1
So 127680-89-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3/c12-9-10-4-5-13-11(8-10)14-6-2-1-3-7-14/h4-5,8H,1-3,6-7H2/p+1
127680-89-1Relevant articles and documents
New pyridine derivatives as potential antimicrobial agents
Klimesova, Vera,Svoboda, Martin,Waisser, Karel,Pour, Milan,Kaustova, Jarmila
, p. 666 - 672 (2007/10/03)
A set of pyridine derivatives bearing a substituted alkylthio chain or a piperidyl ring in position 2 or 4 were synthesized, and their antimycobacterial and antifugal activities were evaluated. Chemical structures were confirmed by IR and NMR data, and by elemental analysis. Minimum inhibitory concentrations (MIC) were used for the evaluation of microbiological activity in vitro. The compounds were moderately active against both Mycobacterium tuberculosis and nontuberculous mycobacteria. The most active compound was 2-cyanomethylthiopyridine-4-carbonitrile (7) with MIC against Mycobacterium kansasii in the range of 8-4 μmol/l. The antifungal activities of the compounds were relatively low. Copyright (C) 1999 Elsevier Science S.A.
Harmful:;
