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CAS

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1277116-18-3

triisopropylsilyl 4-(5-formylfuran-2-yl)-2-(triisopropylsilyloxy)benzoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1277116-18-3 Structure

  • Basic information

    1. Product Name: triisopropylsilyl 4-(5-formylfuran-2-yl)-2-(triisopropylsilyloxy)benzoate
    2. Synonyms:
    3. CAS NO:1277116-18-3
    4. Molecular Formula:
    5. Molecular Weight: 544.879
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1277116-18-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: triisopropylsilyl 4-(5-formylfuran-2-yl)-2-(triisopropylsilyloxy)benzoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: triisopropylsilyl 4-(5-formylfuran-2-yl)-2-(triisopropylsilyloxy)benzoate(1277116-18-3)
    11. EPA Substance Registry System: triisopropylsilyl 4-(5-formylfuran-2-yl)-2-(triisopropylsilyloxy)benzoate(1277116-18-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1277116-18-3(Hazardous Substances Data)

1277116-18-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1277116-18-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,7,1,1 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1277116-18:
(9*1)+(8*2)+(7*7)+(6*7)+(5*1)+(4*1)+(3*6)+(2*1)+(1*8)=153
153 % 10 = 3
So 1277116-18-3 is a valid CAS Registry Number.

1277116-18-3Relevant articles and documents

A Versatile and Practical Synthesis toward the Development of Novel HIV-1 Integrase Inhibitors

Rinaldi, Marta,Tintori, Cristina,Franchi, Luigi,Vignaroli, Giulia,Innitzer, Anna,Massa, Silvio,Este, Jose A.,Gonzalo, Encarna,Christ, Frauke,Debyser, Zeger,Botta, Maurizio

, p. 343 - 352 (2012/01/11)

As a continuation of our previous work, which resulted in the identification of a new hit compound as an HIV-1 integrase inhibitor, three novel series of salicylic acid derivatives were synthesized using three versatile and practical synthetic strategies and were assayed for their capacity to inhibit the catalytic activity of HIV-1 integrase. Biological evaluations revealed that some of the synthesized compounds possess good inhibitory potency in enzymatic assays and are able to inhibit viral replication in MT-4 cells at low micromolar concentrations. Finally, docking studies were conducted to analyze the binding mode of the synthesized compounds within the DNA binding site of integrase in order to refine their structure-activity relationships. Easy as A, B, C: Three new series of salicylic acid derivatives were designed and synthesized to investigate their activity toward HIV-1 integrase. Some of these compounds were obtained with microwave-assisted procedures developed and optimized in our research group, which allowed us to rapidly generate several final compounds of high purity.

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