1277192-52-5Relevant academic research and scientific papers
Total synthesis and biological evaluation of (-)-9-deoxy-englerin a
Ushakov, Dmitry B.,Navickas, Vaidotas,Strobele, Markus,Maichle-Moessmer, Caecilia,Sasse, Florenz,Maier, Martin E.
, p. 2090 - 2093 (2011)
An effective total synthesis of (-)-9-deoxy-englerin (4), an analogue of the natural guaiane sesquiterpene englerin A (1), has been achieved. The synthesis features a transannular epoxide opening to construct the 5,7-fused ring system followed by transannular ether formation with mercury(II) trifluoroacetate.
