127753-23-5Relevant academic research and scientific papers
Vibrational spectroscopic studies and ab initio calculations of 5-methyl-2-(p-methylaminophenyl)benzoxazole
Ambujakshan,Madhavan,Varghese, Hema Tresa,Panicker, C. Yohannan,Temiz-Arpaci, Ozlem,Tekiner-Gulbas, Betul,Yildiz, Ilkay
, p. 782 - 788 (2008)
FT-IR spectra of 5-methyl-2-(p-methylaminophenyl)benzoxazole was recorded and analysed. The vibrational frequencies of the compound have been computed using the Hartree-Fock/6-31G* basis and compared with the experimental values.
Synthesis and microbiological activity of 5-methyl-2-benzoxazoles
Yalcin, I.,Sener, E.,Oezden, T.,Oezden, S.,Akin, A.
, p. 705 - 708 (2007/10/02)
The synthesis and microbiological activity of a series of 5-methyl-2-(p-substituted phenyl)benzoxazoles 7a-7g are described.The in vitro microbiological activity of these compounds was determined against some Gram-positive and Gram-negative bacteria and C albicans.The observed minimum inhibitory concentration (MIC) values of the derivatives were compared to some other 2,5-disubstituted benzoxazoles and clinically used drugs.The in vitro microbiological data showed that the derivatives 7a-7g exhibited a broad spectrum of antibacterial activity and 7a-c and 7g were significantly active against E coli and/or K pneumoniae at an MIC of 6.2 μg/ml.
