127756-65-4Relevant academic research and scientific papers
Lanthanide- and DMSO-Induced Ring Opening of 2-Iminooxetanes: Synthesis of β-Lactams and β-Keto Amides
Barbaro, Gaetano,Battaglia, Arturo,Giorgianni, Patrizia
, p. 1020 - 1025 (2007/10/02)
2-Iminooxetanes (1), generated by lanthanide-catalyzed heterocycloaddition of aldehydes to ketene imines, are versatile synthons for β-lactams (2) and for β-keto amides (3).Conversion of 1 into 2 and 3 can be accomplished by either lanthanide-induced or o
Acyloxylation at the 4-Position of Azetidin-2-ones
Easton, Christopher J.,Love, Stephen G.,Wang, Peng
, p. 277 - 282 (2007/10/02)
The copper-catalysed reaction of azetidin-2-ones with t-butyl perbenzoate or peracetate affords the corresponding 4-benzoyloxy- and acetoxy-substituted β-lactams, respectively.N-Unsubstituted 4-acyloxyazetidinones can be synthesized by dearylation of the N-(4-methoxyphenyl)-substituted products with ceric ammonium nitrate.Acyloxylation of β-lactams that are monosubstituted at C-3 affords predominantly trans-products.
