127813-33-6

Basic information

• Product Name: 2-(pyrimidin-2-ylsulfanyl)aniline
• Synonyms: 2-(pyrimidin-2-ylsulfanyl)aniline
• CAS NO: 127813-33-6
• Molecular Formula: C₁₀H₉N₃S
• Molecular Weight: 203.26356
• Mol File: 127813-33-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(pyrimidin-2-ylsulfanyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(pyrimidin-2-ylsulfanyl)aniline(127813-33-6)
• EPA Substance Registry System: 2-(pyrimidin-2-ylsulfanyl)aniline(127813-33-6)

Safety Data

• Hazardous Substances Data: 127813-33-6(Hazardous Substances Data)

Usage

Description

2-(pyrimidin-2-ylsulfanyl)aniline is a chemical compound with the molecular formula C9H8N4S. It is an aniline derivative containing a pyrimidine ring with a sulfhydryl group attached to the second position of the pyrimidine ring. 2-(pyrimidin-2-ylsulfanyl)aniline is often used in organic synthesis and medicinal chemistry as a building block for creating pharmaceuticals and other organic compounds. Its unique molecular structure and reactivity make it a promising candidate for the development of new drugs and therapeutic agents.

Uses

Used in Organic Synthesis:
2-(pyrimidin-2-ylsulfanyl)aniline is used as a building block for the synthesis of various organic compounds. Its presence in the molecular structure allows for the creation of a wide range of chemical entities, making it a valuable component in the field of organic chemistry.
Used in Medicinal Chemistry:
2-(pyrimidin-2-ylsulfanyl)aniline is used as a key component in the development of pharmaceuticals. Its unique structure and reactivity contribute to the design and synthesis of new drugs and therapeutic agents, potentially leading to breakthroughs in the treatment of various diseases and conditions.
Used in Drug Development:
2-(pyrimidin-2-ylsulfanyl)aniline is used as a starting material in the development of new drugs. Its potential applications in medicinal chemistry make it a valuable resource for researchers and pharmaceutical companies working on the creation of innovative and effective treatments.

Upstream product

• 1722-12-9 2-chloropyrimidine 
• 137-07-5 2-amino-benzenethiol 
• 58696-13-2 2-(2-nitro-phenylsulfanyl)-pyrimidine 

Downstream Products

• 127813-34-7 2-(2-iodophenylthio)pyrimidine 
• 127813-41-6 2-(2-trimethylsilylethynylphenylthio)pyrimidine 

Relevant articles and documents

COMPOUND

There is provided a compound having Formula (I) wherein each of R1, R2, R4, R5, R6 and R7 are independently selected from (a) H, (b) R17, -OC(R17)3, -OCH(R17)2, -(OCH2R)17, -C(R17)3, -CH(R17)2, or -CH2R17 wherein R17 is a halogen; (c) -CN; (d) optionally substituted alkyl, (e) optionally substituted heteroalkyl; (f) optionally substituted aryl; (g) optionally substituted heteroaryl; (h) optionally substituted arylalkyl; (i) optionally substituted heteroarylalkyl; (j) hydroxy; (k) alkoxy; (l) aryloxy; (m) -SO2-alkyl; and (n) -N(R11)C(O)R13; wherein the optional substituents of (d) (e) (f) (h) and (i) are selected from the group consisting of: C1-6 alkyl, halo, cyano, nitro, haloalkyl, hydroxy, alkoxy, carboxy, carboxyalkyl, carboxamide, mercapto, amino, alkylamino, dialkylamino, sulfonyl, sulfonamido, aryl and heteroaryl ; each of rings A and B are selected from five or six membered carbon rings optionally containing one or more hetero atoms selected from N, S, and O and optionally having fused thereto a further ring; X is an optional group selected from O, S, S=O, S(=O)2, C=O, S(=O)2NR8, C=ONR9, NR10, wherein R8, R9 and R10 are independently selected from H and hydrocarbyl, wherein n and p are independently selected from O and 1 ; Y is (R11)1-3 wherein each R11 is independently selected from NR12, CR13R14, S(=O)2 and C=O, wherein R12, R13 and R14 are independently selected from H and hydrocarbyl; Z is selected from (i) six or seven membered ring containing carbon and at least one nitrogen, which may be optionally substituted wherein the substituents may together form further ring fused thereto; and (ii) a -R15-NR16- group wherein R15 is an optionally substituted C1-6 alkyl chain and R16 is selected from H and hydrocarbyl; and R3 is selected from Formula (A).