127818-65-9

Upstream product

• 78707-69-4 3-Methyl-5-(1-methylselanyl-ethyl)-cyclohexanone 
• 40920-68-1 3-methyl-5-ethylcyclohex-2-en-1-one 
• 7214-50-8 5-methylcyclohex-2-en-1-one 
• 925-90-6 ethylmagnesium bromide 
• 109314-83-2 (methyl-5 cyclohexanone yl-3) dithioacetate de methyle 
• 78707-85-4 Trimethyl-[5-methyl-3-(1-methylselanyl-ethyl)-cyclohex-1-enyloxy]-silane 
• 78707-73-0 3-(1,1-Bis-methylselanyl-ethyl)-5-methyl-cyclohexanone 

Relevant academic research and scientific papers

Stereochimie de l'addition-1,4 d'enethiolates de dithioesters aux methyl cyclohexene-2 ones

Lithium dithioacetate, generated by deprotonation with LDA in THF, has been submitted to the action of four methyl 2-cyclohexenones 5-8.Regioselective 1,4-addition has been observed.The two stereoisomeric oxodithioesters of each couple 9-13 have been dist

STEREOCHEMICAL ASSIGMENT BY MASS SPECTROMETRY. DOUBLE BOND GEOMETRICAL ISOMERS OF 3,5-DIALKYLCYCLOHEXYLIDENE ACETIC ACID ESTERS AND 3-ALKYL-2-ALKENOATES

Mass spectrometry is best physical method for the configurational assignment of E- and Z-3,5-dialkylcyclohexylidene acetic acid esters 1 and E- and Z-3-alkyl-2-alkenoates 2.The homoallylic cleavage resulting in the loss of the C-3 and C-5 alkyl groups from 1 and of the two δ-alkyls from 2 is a stereospecific process: the loss of the group which is adjacent to the carbonyl is significantly preferred.The stereospecifity of this fragmentation is interpreted in terms of a hidden hydrogen transfer preceding the carbon-carbon bond cleavage.

STEREOCHEMISTRY OF THE C3 ADDITION OF 1-LITHIO 1,1-BIS METHYLSELENOALKANES TO METHYL CYCLOHEXENONES

The presence of DME or HMPT allows the C3 regio and stereoselective introduction of 1,1-bis methylselenoalkanes to methyl cyclohexenones.The resulting compounds have been stereoselectively transformed to 3-ethyl methyl cyclohexanones.