127865-18-3Relevant academic research and scientific papers
Benzotriazole-assisted synthesis of novel mannich bases from ketones and diverse aldehydes
Katritzky, Alan R.,Harris, Philip A.
, p. 987 - 996 (2007/10/02)
A wide variety of β-amino ketones are prepared in moderate to good yields by the reaction of the lithium enolates of cyclohexanone, acetophenone, α-tetralone and camphor with the readily available adducts from an aldehyde or ketone, an amine and benzotriazole. Some diastereoselectivity is observed when the benzotriazole adduct is derived from benzaldehyde.
