127866-79-9

Basic information

• Product Name: 1H-Tetrazol-5-amine, 1-(2-methylphenyl)-
• CAS NO: 127866-79-9
• Molecular Formula: C8H9N5
• Molecular Weight: 175.193
• Mol File: 127866-79-9.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: 1H-Tetrazol-5-amine, 1-(2-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Tetrazol-5-amine, 1-(2-methylphenyl)-(127866-79-9)
• EPA Substance Registry System: 1H-Tetrazol-5-amine, 1-(2-methylphenyl)-(127866-79-9)

Safety Data

• Hazardous Substances Data: 127866-79-9(Hazardous Substances Data)

Usage

Physical Appearance

White crystalline solid

Solubility

Insoluble in water

Melting Point

Approximately 211-213 degrees Celsius

Uses

Building block in the synthesis of pharmaceuticals and agrochemicals; potential use in the treatment of various medical conditions, including cancer and cardiovascular diseases

Other Properties

Known for its explosive properties and used in the production of explosive materials.

Upstream product

• 101030-88-0 C₈H₁₀N₂O₃S 
• 95-53-4 o-toluidine 
• 94-69-9 2'-methylformanilide 
• 10468-64-1 o-tolyl isocyanide 
• 614-69-7 2-tolyl isothiocyanate 
• 614-78-8 o-tolylthiourea 
• 10532-63-5 N-(o-tolyl)cyanamide 
• 261943-62-8 (1H-tetrazol-5-yl)-o-tolyl-amine 
• 107-21-1 ethylene glycol 
• 4418-61-5 5-aminotetrazole 
• 615-37-2 ortho-methylphenyl iodide 

Downstream Products

• 261943-62-8 (1H-tetrazol-5-yl)-o-tolyl-amine 

Relevant articles and documents

Nano indium oxide as a recyclable catalyst for the synthesis of arylaminotetrazoles

Nano indium oxide is an effective heterogeneous catalyst for the reaction between aryl cyanamides and sodium azide to synthesize the arylaminotetrazoles in good yields. This method has advantages of high yields, simple methodology, short reaction times an

Green chemistry: ZrOCl2·8H2O catalyzed regioselective synthesis of 5-amino-1-aryl-1H-tetrazoles from secondary arylcyanamides in water

A green and efficient method for the synthesis of 5-amino-1-aryl-1H- tetrazoles with excellent yields and high purity from secondary arylcyanamides is described. This method is completely green because no organic solvents or protic acid catalyst is used t

Efficient synthesis of arylaminotetrazoles in water

Arylaminotetrazole derivatives are synthesized efficiently by the reaction of arylcyanamides and sodium azide in the presence of ZnCl2 under aqueous conditions at reflux. Generally, isomer of 5-arylamino-1H-tetrazole can be obtained from arylcy

Application of supported Mn(iii), Fe(iii) and Co(ii) as heterogeneous, selective and highly reusable nano catalysts for synthesis of arylaminotetrazoles, and DFT studies of the products

M@Si/Al (where M = Mn(iii), Co(ii) and Fe(iii) supported on nanosized SiO2/Al2O3) is applied as an efficient, highly reusable and heterogeneous catalyst for the regiospecific synthesis of 1-aryl-5-amino-1H-tetrazole in dim

Iron-promoted sulfur sequestration for the substituent-dependent regioselective synthesis of tetrazoles and guanidines

We have established a facile and versatile synthetic methodology for the construction of tetrazoles and guanidines in the presence of an eco-friendly, inexpensive, easily available iron reagent. Aromatic thioureas with electron-donating substituents produced their respective target products in quantitative yield. In contrast, when electron-withdrawing substituted aromatic thioureas were used, the expected products were obtained in reduced yield. However, the desired products were obtained in good yield at moderate temperature. In addition, mechanistic studies revealed that the synthetic route involved iron-based subsequent reactions of addition and removal of sulfur.

Chitosan supported 1-phenyl-1H-tetrazole-5-thiol ionic liquid copper(II) complex as an efficient catalyst for the synthesis of arylaminotetrazoles

A recyclable functional hybrid catalyst was prepared via a simple method using chitosan as a linear polysaccharide and an ionic liquid. In this work, the synthesis of chitosan supported 1-phenyl-1H-tetrazole-5-thiol ionic liquid copper(II) complex (CS@Tet