127866-81-3

Basic information

• Product Name: 1-(2,6-dimethylphenyl)-5-amino-1H-tetrazole
• Synonyms: 1-(2,6-dimethylphenyl)-5-amino-1H-tetrazole
• CAS NO: 127866-81-3
• Molecular Weight: 189.22
• Mol File: 127866-81-3.mol

Chemical Properties

• CAS DataBase Reference: 1-(2,6-dimethylphenyl)-5-amino-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,6-dimethylphenyl)-5-amino-1H-tetrazole(127866-81-3)
• EPA Substance Registry System: 1-(2,6-dimethylphenyl)-5-amino-1H-tetrazole(127866-81-3)

Safety Data

• Hazardous Substances Data: 127866-81-3(Hazardous Substances Data)

Upstream product

• 20922-60-5 2,6-dimethylphenylcyanamide 
• 4418-61-5 5-aminotetrazole 
• 608-28-6 2,6-dimethyliodobenzene 
• 119072-54-7 2,6-dimethylphenyl isonitrile 
• 25348-91-8 C₉H₁₂N₂O₃S 
• 124111-95-1 C₉H₁₄N₄ 

Relevant articles and documents

Magnetic chitosan-copper nanocomposite: A plant assembled catalyst for the synthesis of amino- and N-sulfonyl tetrazoles in eco-friendly media

A greener, cost efficient and simple method is described to prepare copper nanoparticles (NPs) immobilized on the magnetic chitosan (one of the more versatile polysaccharides) using Euphorbia falcata leaf extract as reducing/stabilizing agent. The prepare

Functionalization of chitosan by grafting Cu(II)-5-amino-1H-tetrazole complex as a magnetically recyclable catalyst for C-N coupling reaction

The functionalization of chitosan (as a linear polysaccharide) with a copper complex to expand the areas of its potential applications is an important scientific task. The present work reports the application of Cu(II)-5-amino-1H-tetrazole complex immobilized on modified magnetic chitosan as an effective catalyst (Fe3O4@Chitosan-Tet-Cu(II)) for C-N bond cross-coupling reaction between 5-aminotetrazole and aryl halides under ligand-free conditions in dioxane solvent. The prepared magnetic nanocatalyst was characterized by FT-IR, EDS, TEM, HRTEM, VSM, FFT, XRD, TG-DTG, ICP-MS, and elemental mapping analyses. 1-Aryl-5-amino-1H-tetrazoles were produced in high yields. The advantages of this catalytic process include simple methodology, avoiding the use of harmful catalysts, short reaction times, excellent yields, easy work-up, and environmentally friendly conditions. Fe3O4@Chitosan-Tet-Cu(II) catalyst exhibited high efficacy and reusability/recyclability even after seven consecutive cycles with low loss of catalytic activity.

Chitosan supported 1-phenyl-1H-tetrazole-5-thiol ionic liquid copper(II) complex as an efficient catalyst for the synthesis of arylaminotetrazoles

A recyclable functional hybrid catalyst was prepared via a simple method using chitosan as a linear polysaccharide and an ionic liquid. In this work, the synthesis of chitosan supported 1-phenyl-1H-tetrazole-5-thiol ionic liquid copper(II) complex (CS@Tet

Selective Gold-Catalysed Synthesis of Cyanamides and 1-Substituted 1H-Tetrazol-5-Amines from Isocyanides

The newly discovered gold-catalysed reaction of isocyanides with hydrazoic acid generated in situ from trimethylsilyl azide and methanol (or, alternatively, from NaN3/AcOH) produces either cyanamides or 1-substituted 1H-tetrazol-5-amines, depending on the amount of available HN3. The reaction proceeds selectively and in generally high yields of either product, thus providing a particularly convenient access to a wide range of substituted 1H-tetrazol-5-amines that are rather difficult to access otherwise.

A versatile synthesis of arylaminotetrazoles by a magnetic Fe@Phendiol@Mn nano-particle catalyst and its theoretical studies

The Fe3O4 magnetic nano-particles were modified with 1,10-phenanthroline-5,6-diol and the relevant Mn complex (Fe@Phendiol@Mn) synthesized as a nano-magnetic heterogeneous catalyst to be used for the synthesis of various arylaminotet

CoFe2O4 nanoparticles as a magnetically recoverable and reusable catalyst for the synthesis of arylaminotetrazoles and 5-aryloxytetrazoles

An efficient and direct method is described for the synthesis of 5-arylamino-1H-tetrazoles (Isomer A) or 1-aryl-5-amino-1Htetrazoles (Isomer B) and 5-aryloxytetrazoles from arylcyanamides or cynates with nano CoFe 2O4 as a reusable a

Synthesis of thiotetrazoles and arylaminotetrazoles using rutile TiO 2 nanoparticles as a heterogeneous and reusable catalyst

A novel method is described to prepare rutile TiO2 nanoparticles which are reusable and efficient heterogeneous catalysts for the synthesis of thiotetrazoles and arylaminotetrazoles - compounds widely used in medicinal and coordination chemistry. This procedure has the advantages of good to excellent yields of products, elimination of homogeneous catalysts and toxic and explosive reagents, simple methodology, easy work up and the reusability of the heterogeneous catalyst.

Application of supported Mn(iii), Fe(iii) and Co(ii) as heterogeneous, selective and highly reusable nano catalysts for synthesis of arylaminotetrazoles, and DFT studies of the products

M@Si/Al (where M = Mn(iii), Co(ii) and Fe(iii) supported on nanosized SiO2/Al2O3) is applied as an efficient, highly reusable and heterogeneous catalyst for the regiospecific synthesis of 1-aryl-5-amino-1H-tetrazole in dim

Nano indium oxide as a recyclable catalyst for the synthesis of arylaminotetrazoles

Nano indium oxide is an effective heterogeneous catalyst for the reaction between aryl cyanamides and sodium azide to synthesize the arylaminotetrazoles in good yields. This method has advantages of high yields, simple methodology, short reaction times an

Ultrasound-promoted regioselective synthesis of 1-aryl-5-amino-1H- tetrazoles

A new method for the regioselective synthesis of 1-aryl-5-amino-1H- tetrazoles has been developed by the reaction of arylcyanamides with sodium azide using ZnClunder ultrasound irradiation in excellent yields. Copyright