127874-66-2

Upstream product

• 1187746-88-8 1,3-di-O-acetyl-2,4-di-O-benzyl-α,β-D-xylopyranose 
• 87-72-9 D-Xylose 
• 18405-04-4 2-methoxyethyl 2,3,4-tri-O-acetyl-β-D-xylopyranoside 
• 1000780-22-2 allyl 3-O-acetyl-2,4-di-O-benzyl-α-D-xylopyranoside 
• 99388-80-4 Acetic acid (2R,3R,4S,5R)-3,5-bis-benzyloxy-2-(2-methoxy-ethoxy)-tetrahydro-pyran-4-yl ester 
• 99388-63-3 2-Methoxyethyl 2,4-di-O-benzyl-β-D-xylopyranoside 

Downstream Products

• 1187746-80-0 3-O-acetyl-2,4-di-O-benzyl-α,β-D-xylopyranose 2-thiopyridyl carbonate 
• 99388-74-6 Benzyl 4-O-(2,4-di-O-benzyl-α-D-xylopyranosyl)-2,3-di-O-benzyl-α-D-xylopyranoside 
• 99388-75-7 Benzyl 4-O-(3-O-acetyl-2,4-di-O-benzyl-α-D-xylopyranosyl)-2,3-di-O-benzyl-α-D-xylopyranoside 

Relevant academic research and scientific papers

Total synthesis and structural revision of the presumed aeruginosins 205A and B

A stereoselective synthesis of enantiopure aeruginosin 205B aglycon confirms the presence of a (3R,2S)-3-chloroleucine amide residue and a (6R)-hydroxy (4aR,7aS)-octahydroindole-(2S)-2-carboxamide (Choi) subunit instead of a 6-chloro-substituted core (Cco

Stereoselective synthesis of the 3-aminopropyl glycosides of α-D-xyl-(1→3)-β-D-glc and α-D-xyl-(1→3)-α-D- xyl-(1→3)-β-D-glc and of their corresponding N-octanoyl derivatives

The stereoselective synthesis of the spacer-armed disaccharide α-D-Xyl-(1→3)-β-D-Glc-O-(CH2)3NH 2 and trisaccharide α-D-Xyl-(1→3)-α-D-Xyl-(1→3) -β-D-Glc-O-(CH2)3NH2, as well as of their N-octanoyl derivatives, was performed for their subsequent use as acceptors and reference samples in xylosyltransferase assays. These structures are found as O-linked glycans on epidermal growth factor (EGF) domains of several blood-clotting factors and Notch. The target products were prepared by glycosylation with a 3-O-acetylated xylosyl donor that was previously found to be an effective α-xylosylating agent. However, in this paper we show that the structure of the glycosyl acceptor could influence the stereochemical results of the glycosylation and even lead to reversed stereoselectivity in the case of one acceptor. Georg Thieme Verlag Stuttgart.

Pentoside Synthesis by Dehydrative Glykosylation. Synthesis of O-α-L-Arabinofuranosyl-(1-3)-O-β-D-xylopyranosyl-(1-4)-D-xylopyranose

O-α-L-Arabinofuranosyl-(1-3)-O-β-D-xylopyranosyl-(1-4)-D-xylopyranose isolated from the hydrolyzate of corncobs arabinoxylan was synthesized by way of dehydrative glycosylation.