127900-46-3

Upstream product

• 623-51-8 ethyl 2-sulfanylacetate 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 

Downstream Products

• 127900-54-3 (3-Phenyl-prop-2-yne-1-sulfonyl)-acetic acid 
• 127900-66-7 4,4-Dioxo-6-[1-phenyl-meth-(Z)-ylidene]-4λ⁶-[1,4]oxathian-2-one 
• 127900-60-1 6-[1-Phenyl-meth-(E)-ylidene]-[1,4]oxathian-2-one 
• 127900-50-9 (3-Phenyl-prop-2-ynylsulfanyl)-acetic acid 

Relevant academic research and scientific papers

Cyclization of Alkynecarboxylic Acids: Synthesis and Reactions of 6-Methylene-1,4-oxathian-2-ones and Their 4,4-Dioxides

In the presence of mercury(II) oxide, (2-propynylthio)acetic acids (3a)-(3e) cyclised to 6-methylene-1,4-oxathian-2-ones (8a)-(8e) in moderate yields.Similarly, (2-propynylsulfonyl)acetic acids (6a)-(6e) also gave 6-methylene-2-oxo-1,4-oxathiane 4,4-dioxides (9a)-(9e).Treatment of oxathian-2-one (8a) and its -4,4-dioxide (9a) with p-toluenesulfonic acid in refluxing benzene gave isomerised products (11a) and (12a) respectively.However, treatment of (8a) and (9a) with p-toluenesulfonic acid in refluxing methanol did not give cyclic adducts (13a) and (14a) but instead good yields of ring-opened methyl esters (15a) and (16a).