1279034-98-8

Basic information

• Product Name: (2S,4R)-4-((tert-butoxycarbonyl)aMino)pyrrolidine-2-carboxylic acid
• Synonyms: (2S,4R)-4-((tert-butoxycarbonyl)aMino)pyrrolidine-2-carboxylic acid;(4R)-4-(Boc-aMino)-L-proline
• CAS NO: 1279034-98-8
• Molecular Formula: C10H18N2O4
• Molecular Weight: 230.26092
• Mol File: 1279034-98-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 403.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.20±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 2.18±0.40(Predicted)
• CAS DataBase Reference: (2S,4R)-4-((tert-butoxycarbonyl)aMino)pyrrolidine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-4-((tert-butoxycarbonyl)aMino)pyrrolidine-2-carboxylic acid(1279034-98-8)
• EPA Substance Registry System: (2S,4R)-4-((tert-butoxycarbonyl)aMino)pyrrolidine-2-carboxylic acid(1279034-98-8)

Safety Data

• Hazardous Substances Data: 1279034-98-8(Hazardous Substances Data)

Usage

Description

(2S,4R)-4-((tert-butoxycarbonyl)amino)pyrrolidine-2-carboxylic acid is a chemical compound with a molecular formula of C9H17N2O4. It is a derivative of pyrrolidine-2-carboxylic acid, featuring a tert-butoxycarbonyl (Boc) protected amino group at the 4-position. (2S,4R)-4-((tert-butoxycarbonyl)amino)pyrrolidine-2-carboxylic acid is characterized by its chiral centers at the 2nd and 4th positions, with the specific configuration of 2S,4R. It is widely recognized for its role as a chemical building block in organic synthesis and pharmaceutical research.

Uses

Used in Pharmaceutical Research:
(2S,4R)-4-((tert-butoxycarbonyl)amino)pyrrolidine-2-carboxylic acid is used as an intermediate in the synthesis of peptides for drug development. Its Boc-protected amino group allows for the controlled assembly of peptide sequences, facilitating the creation of complex bioactive molecules with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, (2S,4R)-4-((tert-butoxycarbonyl)amino)pyrrolidine-2-carboxylic acid serves as a versatile building block for the construction of various organic compounds. The Boc group can be selectively removed under mild acidic conditions, enabling the introduction of different functional groups and the synthesis of diverse molecular architectures.
Used in Biological Research:
(2S,4R)-4-((tert-butoxycarbonyl)amino)pyrrolidine-2-carboxylic acid is also utilized in biological research as a component of peptides that can interact with biological targets, such as enzymes, receptors, or other proteins. This allows researchers to study the structure-activity relationships of these peptides and their potential as bioactive agents.
Used in Peptide Synthesis:
In the synthesis of peptides, (2S,4R)-4-((tert-butoxycarbonyl)amino)pyrrolidine-2-carboxylic acid is used as a protected amino acid building block. The Boc group protects the amino group from unwanted side reactions during the assembly of the peptide chain, ensuring the correct sequence and integrity of the final product. Once the peptide synthesis is complete, the Boc group can be removed to reveal the free amino group, allowing for further modifications or functionalization of the peptide.