1279037-47-6

Basic information

• Product Name: (S)-3-{[5-((cyclopropylmethyl)amino)-1-phenyl-1H-pyrazole-3-carbonyl]amino}-3-(o-tolyl)propionic acid
• Synonyms: (S)-3-{[5-((cyclopropylmethyl)amino)-1-phenyl-1H-pyrazole-3-carbonyl]amino}-3-(o-tolyl)propionic acid
• CAS NO: 1279037-47-6
• Molecular Weight: 418.495
• Mol File: 1279037-47-6.mol

Chemical Properties

• CAS DataBase Reference: (S)-3-{[5-((cyclopropylmethyl)amino)-1-phenyl-1H-pyrazole-3-carbonyl]amino}-3-(o-tolyl)propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-{[5-((cyclopropylmethyl)amino)-1-phenyl-1H-pyrazole-3-carbonyl]amino}-3-(o-tolyl)propionic acid(1279037-47-6)
• EPA Substance Registry System: (S)-3-{[5-((cyclopropylmethyl)amino)-1-phenyl-1H-pyrazole-3-carbonyl]amino}-3-(o-tolyl)propionic acid(1279037-47-6)

Safety Data

• Hazardous Substances Data: 1279037-47-6(Hazardous Substances Data)

Upstream product

• 736131-48-9 (S)-3-amino-3-(2-methylphenyl)propionic acid 
• 1391944-57-2 5-((cyclopropylmethyl)amino)-1-phenyl-1H-pyrazole-3-carboxylic acid 
• 1391944-59-4 5-(bis-(cyclopropyl-methyl)-amino)-1-phenyl-1H-pyrazole-3-carboxylic acid 
• 866837-96-9 5-amino-3-ethoxycarbonyl-1-phenylpyraole 
• 1053164-76-3 5-amino-1-phenyl-1H-pyrazole-3-carboxylic acid 
• 1489-69-6 Cyclopropanecarboxaldehyde 

Relevant articles and documents

AMINO-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

The present invention relates to compounds of the formula I, wherein A, D, E, G, R10, R11, R30, R40, R50 and R60 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease cathepsin A, and are useful for the treatment of diseases such as atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.

AMINO-SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

Amino-substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals The present invention relates to compounds of the formula (I), wherein A, D, E, G, R10 R11, R30 R40 R50