1279102-38-3Relevant academic research and scientific papers
N-tert-butyl triazolylidenes: Catalysts for the enantioselective (3+2) annulation of α,β-unsaturated acyl azoliums
Candish, Lisa,Forsyth, Craig M.,Lupton, David W.
, p. 9149 - 9152 (2013)
But(yl) not futile: A range of N-tert-butyl-substituted triazolylidene N-heterocyclic carbenes have been prepared. Of these, the morpholinone-derived catalyst (1) proved best suited to the enantioselective synthesis of cyclopentanes from donor-acceptor cy
N-heterocyclic carbene-catalyzed Ireland-Coates claisen rearrangement: Synthesis of functionalized β-lactones
Candish, Lisa,Lupton, David W.
supporting information, p. 58 - 61 (2013/02/25)
The N-heterocyclic carbene (NHC)-catalyzed Claisen rearrangement of hybrid Ireland-Coates structures has been achieved, allowing the stereoselective synthesis of highly functionalized β-lactones. The reaction proceeds with high diastereoselectivity (>20:1
N-heterocyclic carbene-catalyzed (4 + 2) cycloaddition/decarboxylation of silyl dienol ethers with α,β-unsaturated acid fluorides
Ryan, Sarah J.,Candish, Lisa,Lupton, David W.
supporting information; experimental part, p. 4694 - 4697 (2011/05/28)
Herein we report the first all-carbon N-heterocyclic carbene-catalyzed (4 + 2) cycloaddition. The reaction proceeds with α,β-unsaturated acid fluorides and silyl dienol ethers and produces 1,3-cyclohexadienes with complete diastereocontrol (dr >20:1) while demonstrating a new type of reaction cascade exploiting α,β-unsaturated acyl azoliums.
