127911-13-1 Usage
General Description
(1R,4S,8R)-3,8-dimethyl-2-azabicyclo[2.2.2]oct-2-en-5-one, also known as (-)-nicotine, is a heterocyclic compound and the principal alkaloid found in tobacco. It is a highly addictive stimulant that affects the central nervous system, and is one of the main factors contributing to tobacco addiction. Nicotine acts as a nicotinic acetylcholine receptor agonist, which leads to the release of neurotransmitters such as dopamine and norepinephrine. Its effects on the body include increased heart rate, blood pressure, and alertness, as well as potential long-term health risks such as cardiovascular and respiratory diseases, cancer, and reproductive issues. Despite these health risks, nicotine is commonly used in tobacco products such as cigarettes, cigars, and electronic cigarettes.
Check Digit Verification of cas no
The CAS Registry Mumber 127911-13-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,9,1 and 1 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 127911-13:
(8*1)+(7*2)+(6*7)+(5*9)+(4*1)+(3*1)+(2*1)+(1*3)=121
121 % 10 = 1
So 127911-13-1 is a valid CAS Registry Number.
127911-13-1Relevant articles and documents
Synthesis of isoquinuclidinones via a tandem amination/imination sequence: Application to the synthesis of (-)-mearsine
Cuthbertson, James D.,Godfrey, Andrew A.,Taylor, Richard J.K.
, p. 2024 - 2027 (2011/05/09)
The facile synthesis of a range of novel isoquinuclidinones from 6-acyl-cyclohex-2-enones is described, employing aqueous ammonia in a one-pot procedure involving initial conjugate addition of ammonia followed by cyclisation via intramolecular imine forma
