1279128-76-5Relevant articles and documents
Synthesis of N-alkylated noeurostegines and evaluation of their potential as treatment for Gaucher's disease
Rasmussen, Tina S.,Allman, Sarah,Twigg, Gabriele,Butters, Terry D.,Jensen, Henrik H.
, p. 1519 - 1522 (2011)
The potent and selective inhibitor of β-glucosidases, noeurostegine, was evaluated as an inhibitor of glucocerebrosidase (GCase) to give an IC 50 value of 0.4 μM, being 250- and 150-fold better than N-butyl and N-nonyl noeurostegine, respective