127913-27-3Relevant articles and documents
Novel Synthesis of syn-α,β-Epoxy Alcohols by Diastereoselective Carbonyl Reduction of α,β-Epoxy Ketones
Kawakami, Takayo,Shibata, Ikuya,Baba, Akio,Matsuda, Haruo,Sonoda, Noboru
, p. 8625 - 8626 (1994)
A novel tin hydride reagent, Bu3SnH-Bu4NCN, reduced α,β-epoxy ketones to the corresponding syn-α,β-epoxy alcohols in high diastereoselectivities.
Divergent stereoselectivity in the reduction of α,β-epoxy ketones using hydridosilicates
Hojo, Makoto,Fujii, Atsuko,Murakami, Chikara,Aihara, Hidenori,Hosomi, Akira
, p. 571 - 574 (2007/10/02)
α,β-Epoxy ketones are reduced by trimethoxysilane in the presence of a catalytic amount of lithium melboxide to yield the corresponding alcohols. This reaction system reveals divergent selectivity depending on the solvent; both anti-selectivity and syn-se
Enzymatic Preparation of Chiral 1-Phenylglycidols and 1-Phenyl-1,2-propanediols
Takeshita, Mitsuhiro,Yaguchi, Reiko,Akutsu, Nami
, p. 1369 - 1372 (2007/10/02)
Asymmetric synthesis of chiral 1-phenylglycidols and the O-acetates, which were expected to be useful intermediates for the synthesis of β-blockers, has been achieved effectively by use of baker's yeast and lipase PS.These chiral epoxides could be reduced regioselectively with lithium aluminium hydride to give chiral 1-phenyl-1,2-propanediols.
STEREOSELECTIVE INTRODUCTION OF CHIRAL CENTRES IN ACYCLIC PRECURSORS: A PROBE INTO THE TRANSITION STATE OF V5+-CATALYZED t-BUTYLHYDROPEROXIDE (TBHP) EPOXIDATION OF ACYCLIC ALLYLIC ALCOHOLS AND ITS SYNTHETIC IMPLICATIONS.
Narula, Acharan S.
, p. 5579 - 5582 (2007/10/02)
Utility of the (Me)3Si-group for manipulating the relative energies of the diastereomeric transition states for V5+-catalyzed TBHP epoxidations of acyclic allylic alcohols is presented.
