1279220-43-7

Basic information

• Product Name: FOSINOPRILAT-D7
• Synonyms: FOSINOPRILAT-D7
• CAS NO: 1279220-43-7
• Molecular Formula: C23H27D7NO5P
• Molecular Weight: 442.54
• Mol File: 1279220-43-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: FOSINOPRILAT-D7(CAS DataBase Reference)
• NIST Chemistry Reference: FOSINOPRILAT-D7(1279220-43-7)
• EPA Substance Registry System: FOSINOPRILAT-D7(1279220-43-7)

Safety Data

• Hazardous Substances Data: 1279220-43-7(Hazardous Substances Data)

Usage

Description

Fosinoprilat-D7 is a labeled analogue of Fosinoprilat (F727815), which is a metabolite of Fosinopril (F727800). Fosinopril is a phosphinic acid containing angiotensin-converting enzyme (ACE) inhibitor. Fosinoprilat-D7 is used in various applications due to its unique properties and functions.

Uses

Used in Pharmaceutical Industry:
Fosinoprilat-D7 is used as a research tool for studying the pharmacokinetics, metabolism, and mechanism of action of Fosinopril and its metabolite, Fosinoprilat. It helps in understanding the drug's absorption, distribution, metabolism, and excretion (ADME) properties, which are crucial for drug development and optimization.
Used in Drug Metabolism Studies:
Fosinoprilat-D7 is used as a labeled internal standard in liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS) assays. It aids in the quantification and identification of Fosinopril and its metabolites in biological samples, such as blood, plasma, and urine, ensuring accurate and reliable results.
Used in Quality Control:
Fosinoprilat-D7 is used as a reference material in the quality control of pharmaceutical products containing Fosinopril. It helps in verifying the purity, potency, and stability of the drug, ensuring that it meets the required standards and is safe for use.
Used in Toxicology Studies:
Fosinoprilat-D7 is used in toxicological research to investigate the potential toxic effects of Fosinopril and its metabolites. This information is vital for assessing the safety profile of the drug and determining the appropriate dosage and administration guidelines.
Used in Drug Interaction Studies:
Fosinoprilat-D7 is used to study the potential interactions between Fosinopril and other drugs or substances. This helps in understanding the possible side effects, contraindications, and drug-drug interactions, which are essential for the safe and effective use of the medication.