127925-91-1

Basic information

• Product Name: 1-(4-Iodo-phenyl)-2-(2-methyl-4,5-dinitro-imidazol-1-yl)-ethanone
• CAS NO: 127925-91-1
• Molecular Weight: 416.132
• Mol File: 127925-91-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-Iodo-phenyl)-2-(2-methyl-4,5-dinitro-imidazol-1-yl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Iodo-phenyl)-2-(2-methyl-4,5-dinitro-imidazol-1-yl)-ethanone(127925-91-1)
• EPA Substance Registry System: 1-(4-Iodo-phenyl)-2-(2-methyl-4,5-dinitro-imidazol-1-yl)-ethanone(127925-91-1)

Safety Data

• Hazardous Substances Data: 127925-91-1(Hazardous Substances Data)

Upstream product

• 19183-16-5 2-methyl-4,5-dinitroimidazole 
• 31827-94-8 2-bromo-1-(4-iodophenyl)ethanone 

Relevant articles and documents

Azoles. 27. Nitroimidazole derivatives, their antibacterial and fungicidal activity and electron affinity

Nitroimidazole derivatives 3a-3g, 4a-4g and 5-8 were synthesized by treating 4,5-dinitro- and 2-methyl-4,5-dinitroimidazole (1,2) with phenacyl bromide, its p-substituted derivatives or epichlorohydrin. 1-(3-Chloro-2-hydroxypropyl)-4,5-dinitroimidazole (5) and its 2-methyl derivative 6 have been converted to imidazo-oxazoles 7 and 8 or amino imidazole derivatives 9-14 by the action of potassium carbonate or cyclic amines (pyrrolidine, piperidine, morpholine and N-methylpiperazine). Some of the newly synthesized nitroimidazole derivatives show antibacterial and fungicidal activity. The electron affinity of the nitroimidazole derivatives 1-24 is discussed on the basis of their half-wave potentials and in the connection with their eventual radiosensitizing properties.