127927-60-0Relevant academic research and scientific papers
Ring opening of nonactivated 2-(1-aminoalkyl) aziridines: Unusual regio- and stereoselective C-2 and C-3 cleavage
Concellon, Jose M.,Riego, Estela
, p. 6407 - 6410 (2007/10/03)
We have studied the ring opening of nonactivated amino aziridines 1 by water under acidic conditions. Depending on the acid used, amino aziridines are cleaved at C-3 or C-2 with high regioselectivity, and total stereoselectivity, affording chiral 2,3-diam
PROTECTIVE GROUP TUNING IN THE STEREOSELECTIVE CONVERSION OF α-AMINO ALDEHYDES INTO AMINOALKYL EPOXIDES
Reetz, M.T.,Binder, J.
, p. 5425 - 5428 (2007/10/02)
Sulfonium and arsonium ylides of the type CH2=S(CH3)2 and CH2=As(Ph)3 react with doubly protected α-amino aldehydes 1 derived from amino acids to form aminoalkyl epoxides 3/4, diastereofacial selectivity ranging between 86:14 and >95:5.
