127945-78-2 Usage
Properties
1. Molecular formula: C12H14N4O4
2. Pyrimidine derivative with a substituted amino group and a carbonitrile functional group
Specific content
1. Potential inhibitor of dihydroorotate dehydrogenase
2. Involved in de novo pyrimidine biosynthesis pathway
3. Potential therapeutic agent for cancer and autoimmune disorders
4. Complex structure
5. Potential pharmaceutical applications
6. Interesting target for further research and development
Check Digit Verification of cas no
The CAS Registry Mumber 127945-78-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,9,4 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 127945-78:
(8*1)+(7*2)+(6*7)+(5*9)+(4*4)+(3*5)+(2*7)+(1*8)=162
162 % 10 = 2
So 127945-78-2 is a valid CAS Registry Number.
127945-78-2Relevant academic research and scientific papers
Synthesis and Antivirial Activity of Some Acyclic and C-Acyclic Pyrrolopyrimidine Nucleoside Analogues
Bennett, Sharon M.,Nguyen-Ba, Nghe,Ogilvie, Kelvin K.
, p. 2162 - 2173 (2007/10/02)
A series of acyclic and C-acyclic 7-deazapurine nucleosides have been synthesized and tested for antivirial activity.Reaction of the sodium salt of 2-amino-3,4-bis(aminocarbonyl)-5-(methylthio)pyrrole (6) with an appropriate electrophile gave pyrrole nucl
