Welcome to LookChem.com Sign In|Join Free
  • or
MDL 74156, also known as Hydrodolasetron, is the reduced form of Dolasetron (D528500), which is a specific serotonin (5HT3) receptor antagonist. It is characterized by its ability to block the action of serotonin on the 5HT3 receptors, making it a potential candidate for various pharmaceutical applications.

127951-99-9

Post Buying Request

127951-99-9 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

127951-99-9 Usage

Uses

Used in Pharmaceutical Industry:
MDL 74156 is used as an antiemetic agent for the treatment of nausea and vomiting. Its mechanism of action involves blocking the serotonin receptors in the gastrointestinal tract, which helps to alleviate the symptoms of nausea and vomiting. This makes it a valuable asset in the management of various conditions that cause these symptoms, such as chemotherapy-induced nausea and vomiting, postoperative nausea and vomiting, and motion sickness.
In addition to its use as an antiemetic, MDL 74156 may also have potential applications in other areas of the pharmaceutical industry, such as the development of new drugs targeting the serotonin system for the treatment of other conditions. Further research and development are needed to explore these possibilities and fully understand the potential of MDL 74156 in the pharmaceutical field.

Check Digit Verification of cas no

The CAS Registry Mumber 127951-99-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,9,5 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 127951-99:
(8*1)+(7*2)+(6*7)+(5*9)+(4*5)+(3*1)+(2*9)+(1*9)=159
159 % 10 = 9
So 127951-99-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H22N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,9,11-14,18,20,22H,5-8,10H2

127951-99-9Upstream product

127951-99-9Downstream Products

127951-99-9Related news

Characterization of the novel 5-HT3 antagonists MDL 73147EF (dolasetron mesilate) and MDL 74156 (cas 127951-99-9) in NG108-15 neuroblastoma × glioma cells08/21/2019

In radioligand binding experiments, MDL 73147EF and MDL 74156 inhibited the binding of [3H]GR65630 to 5-hydroxytryptamine3 (5-HT3) binding sites on membranes prepared from NG108-15 neuroblastoma × glioma cells. The calculated dissociation constants (KI) were 20.03 ± 6.58 and 0.44 ± 0.18 nM, r...detailed

127951-99-9Relevant academic research and scientific papers

Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of cardiac arrhythmia

-

, (2008/06/13)

The present invention is directed to the use of heterocyclic esters of hexahydro-8-hydroxy-2,6-methano-2H--quinolizin-3(4H)-ones and hexahydro-B-hydroxy-2,6-methano--2H-quinolizines in the manufacture of cardiac antiarrhythmic agents

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 127951-99-9