127953-94-0Relevant academic research and scientific papers
DABCO-promoted synthesis of pyrazoles from tosylhydrazones and nitroalkenes
Tang, Meng,Zhang, Wen,Kong, Yuanfang
supporting information, p. 6250 - 6254 (2013/09/23)
An efficient synthesis of pyrazoles from tosylhydrazones and nitroalkenes was developed. In comparison with the previously reported 1,3-dipolar cycloaddition reaction of diazo compounds with electron-deficient alkenes or alkynes, this methodology proceeded with a sequential Baylis-Hillman/ intramolecular cyclization mechanism and a variety of reversed regioselectivity products were prepared in good yields.
C-H bonds as ubiquitous functionality: A general approach to complex arylated pyrazoles via sequential regioselective C-arylation and N-alkylation enabled by SEM-group transposition
Goikhman, Roman,Jacques, Teresa L.,Sames, Dalibor
supporting information; experimental part, p. 3042 - 3048 (2009/09/04)
Pyrazoles are important azole heteroarenes frequently found in pharmaceuticals and protein ligands, and there has been a growing interest in newsynthetic methods for their preparation. We report the first catalytic intermolecular C-H arylation of pyrazole
