127997-06-2

Basic information

• Product Name: tert-butyl (4R)-4-{(R)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
• CAS NO: 127997-06-2
• Molecular Formula: C₁₅H₂₃NO₆
• Molecular Weight: 313.3462
• Mol File: 127997-06-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 476.7°C at 760 mmHg
• Flash Point: 242.1°C
• Density: 1.228g/cm³
• Vapor Pressure: 4.35E-11mmHg at 25°C
• Refractive Index: 1.516
• CAS DataBase Reference: tert-butyl (4R)-4-{(R)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (4R)-4-{(R)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate(127997-06-2)
• EPA Substance Registry System: tert-butyl (4R)-4-{(R)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate(127997-06-2)

Safety Data

• Hazardous Substances Data: 127997-06-2(Hazardous Substances Data)

Usage

General Description

The chemical "tert-butyl (4R)-4-{(R)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate" is a complex compound with a tert-butyl group attached to an oxazolidine-3-carboxylate structure. The molecule also contains a hydroxy group and a dihydrofuran ring, making it a highly functionalized compound. The stereochemistry of the molecule is also specified, with the (4R) and (R) configurations denoting the positions of the substituents on the oxazolidine and hydroxy moieties, respectively. tert-butyl (4R)-4-{(R)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate may have potential applications in pharmaceuticals, organic synthesis, or materials science due to its unique structure and functional groups.

Upstream product

• 61550-02-5 (furan-2-yloxy)-trimethylsilane 
• 95715-87-0 (R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine 
• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Downstream Products

• 136489-92-4 (S)-tert-Butoxycarbonylamino-((2R,3R,4R,5R,6S)-3,4,5,6-tetraacetoxy-tetrahydro-pyran-2-yl)-acetic acid methyl ester 
• 135086-50-9 (R)-2,2-Dimethyl-4-[(R)-((2R,3R,4R)-5-oxo-3,4-bis-trimethylsilanyloxy-tetrahydro-furan-2-yl)-trimethylsilanyloxy-methyl]-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

THE FOUR-CARBON ELONGATION OF THREE-CARBON CHIRAL SYNTHONS USING 2-(TRIMETHYLSILOXY)FURAN: HIGHLY STEREOCONTROLLED ENTRY TO ENANTIOMERICALLY PURE SEVEN-CARBON α,β-UNSATURATED 2,3-DIDEOXYALDONOLACTONES

The BF3-promoted addition of 2-(trimethylsiloxy)furan to three carbon synthons derived from D- and L-glyceraldehyde, D- and L-serinal, and imines thereof furnishes C7 α,β-unsaturated 2,3-dideoxy-aldonolactone derivatives in high yield, with very high level of diastereoselection.In all the cases, compounds having 4,5-threo:5,6-erythro relative stereodisposition preferentially emerge from the reactions, accompanied by only marginal amounts of 4,5-erythro:5,6-threo epimers.An empirical rule for the rapid assignment of the configuration at C-4 (γ-carbon) of γ-substituted unsaturated and saturated β-butyrolactones is given, based upon the sign of the optical rotation values.