128014-48-2Relevant academic research and scientific papers
IBX works efficiently under solvent free conditions in ball milling
Achar, Tapas Kumar,Maiti, Saikat,Mal, Prasenjit
, p. 12834 - 12839 (2014)
IBX (2-iodoxybenzoic acid), discovered in 1893, is an oxidant in synthetic chemistry whose extensive use is impeded by its explosiveness at high temperature and poor solubility in common organic solvents except DMSO. Since the discovery of Dess-Martin Periodinane in 1983, several modified IBX systems have been reported. However, under ball milling conditions, IBX works efficiently with various organic functionalities at ambient temperature under solvent free conditions. Also, the waste IBA (2-iodosobenzoic acid) produced from the reactions was in situ oxidized to IBX in the following step using oxone and thus reused for multiple cycles by conserving its efficiency (only ～6% loss after 15 cycles). This work describes an overview of a highly economical synthetic methodology which overcomes the problems of using IBX, efficiently in gram scale and in a non-explosive way. This journal is the Partner Organisations 2014.
An aerobic oxidation of alcohols into carbonyl synthons using bipyridyl-cinchona based palladium catalyst
Cheedarala, Ravi Kumar,Chidambaram, Ramasamy R.,Siva, Ayyanar,Song, Jung Il
, p. 32942 - 32954 (2021/12/02)
We have reported an aerobic oxidation of primary and secondary alcohols to respective aldehydes and ketones using a bipyridyl-cinchona alkaloid based palladium catalytic system (PdAc-5) using oxygen at moderate pressure. ThePdAc-5catalyst was analysed using SEM, EDAX, and XPS analysis. The above catalytic system is used in experiments for different oxidation systems which include different solvents, additives, and bases which are cheap, robust, non-toxic, and commercially available on the industrial bench. The obtained products are quite appreciable in both yield and selectivity (70-85%). In addition, numerous important studies, such as comparisons with various commercial catalysts, solvent systems, mixture of solvents, and catalyst mole%, were conducted usingPdAc-5. The synthetic strategy of oxidation of alcohol into carbonyl compounds was well established and all the products were analysed using1H NMR,13CNMR and GC-mass analyses.
Steric and electron-withdrawing effects of substituents governing chemical stability and catalytic activity of Mn(III)-tetraarylporphyrins in HOCl/ClO- alkene epoxidations
Banfi, S.,Montanari, F.,Quici, S.
, p. 117 - 122 (2007/10/02)
Mn(III)-tetrakis(2,4,6-trimethyl-3,5-dihalogenophenyl)porphyrins 5-7 (halogen = Cl, Br, I) have been synthesized and their catalytic activity has been tested in HOCl/ClO- alkene epoxidations.These porphyrins are characterized by structural sepa
