1280219-35-3Relevant academic research and scientific papers
A [3 +2] Dipolar cycloaddition route to 3-hydroxy-3-alkyl oxindoles: An approach to pyrrolidinoindoline alkaloids
Singh, Anand,Roth, Gregory P.
, p. 2118 - 2121 (2011)
A [3+2] cycloaddition approach to the 3-hydroxy-3-alkyl oxindole scaffold is described. Isoxazolines obtained by cycloaddition of nitrile oxide 3 with 3-methylene oxindoles were elaborated to 3-hydroxy-3-cyanomethyl oxindoles employing a one-pot protocol
