128037-06-9Relevant articles and documents
The Synthesis and Transformations of 2-Ethoxycarbonyl-3-isothiocyanatopyridine. Pyridopyrimidines and some Azolopyridopyrimidines
Urleb, Uros,Stanovnik,Branko,Tisler, Miha
, p. 407 - 412 (2007/10/02)
2-Ethoxycarbonyl-3-isothiocyanatopyridine (2), prepared from 3-amino-2-ethoxycarbonylpyridine (1) by the thiophosgene method, was converted with nucleophiles into pyridopyrimidine derivatives 6-11 and 25-30 either directly, or through thiourethane 3.Tricyclic systems 18 and 19 were obtained from 3, and tricyclic systems 12-17 from pyridopyrimidine derivative 11.Pyrrole reacted with 2 at C2 to give 20, and by further cyclization 21 and 22.