1280479-73-3

Basic information

• Product Name: C₂₉H₃₇Cl₂FN₄O₂
• CAS NO: 1280479-73-3
• Molecular Weight: 563.543
• Mol File: 1280479-73-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₉H₃₇Cl₂FN₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₃₇Cl₂FN₄O₂(1280479-73-3)
• EPA Substance Registry System: C₂₉H₃₇Cl₂FN₄O₂(1280479-73-3)

Safety Data

• Hazardous Substances Data: 1280479-73-3(Hazardous Substances Data)

Upstream product

• 846060-58-0 (-)-1-(3,4-dichlorophenyl)-3-oxa-bicyclo[3.1.0]hexan-2-one 
• 846060-70-6 (1S,2R)-1-(3,4-dichlorophenyl)-2-hydroxymethylcyclopropanecarboxylic acid (4-fluorobenzyl)methylamide 
• 4892-89-1 4-(2-(piperazin-1-yl)ethyl)morpholine 
• 1280478-81-0 C₁₉H₁₉Cl₂NO₂ 
• 267409-96-1 3',4'-Dichlorphenylessigsaeureallylester 
• 405-66-3 (4-Fluoro-benzyl)-methyl-amine 

Relevant articles and documents

Identification of a new series of non-peptidic NK3 receptor antagonists

The identification and structure-activity relationships of 2-aminomethyl-1-aryl cyclopropane carboxamides as novel NK3 receptor antagonists are reported. The compound series was optimized to give analogues with low nanomolar binding to the NK3 receptor and brain exposure, leading to activity in vivo in the senktide-induced hypoactivity model in gerbils.