128050-93-1 Usage
General Description
(+)-Ci-cdp1 is a chemical compound that is a potent inhibitor of the phosphatase activity of Cdc25A, a key regulator of the cell cycle. It is known to have therapeutic potential in the treatment of cancer, as it has been shown to induce G1 arrest and suppress the growth of cancer cells. The compound has also been found to have anti-inflammatory properties, as it inhibits the activity of NF-κB, a transcription factor that plays a key role in the immune response. Additionally, (+)-Ci-cdp1 has been studied for its potential role in protecting neurons from oxidative stress and has been found to have neuroprotective effects. Overall, (+)-Ci-cdp1 shows promise as a multifunctional compound with potential applications in cancer treatment, anti-inflammation, and neuroprotection.
Check Digit Verification of cas no
The CAS Registry Mumber 128050-93-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,0,5 and 0 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 128050-93:
(8*1)+(7*2)+(6*8)+(5*0)+(4*5)+(3*0)+(2*9)+(1*3)=111
111 % 10 = 1
So 128050-93-1 is a valid CAS Registry Number.
InChI:InChI=1/C21H18N4O3/c22-20(28)24-6-4-13-14-8-16(23-15(14)1-2-17(13)24)19(27)25-10-11-9-21(11)5-3-12(26)7-18(21)25/h1-3,5,7-8,11,23H,4,6,9-10H2,(H2,22,28)
128050-93-1Relevant articles and documents
Synthesis of N-(phenylsulfonyl)-CI, N-((tert-butyloxy)carbonyl)-CI, CI-CDPI 1, and CI-CDPI 2: CC-1065 functional analogues incorporating the parent 1,2,7,7a-tetrahydrocycloprop[1,2-c]indol-4-one (CI) left-hand subunit
Boger, Dale L.,Wysocki Jr., Ronald J.,Ishizaki, Takayoshi
, p. 5230 - 5240 (2007/10/02)
Full details of the synthesis of N-(phenylsulfonyl)- and N-((tert-butyloxy)carbonyl)-1,2,7,7a-tetrahydrocycloprop[1,2-c]indol-4-one [N-(phenylsulfonyl)-CI (9) and N-BOC-CI (10)] constituting stable derivatives of the parent cyclopropylcyclohexadienone rin