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Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-4-Bromo-3-Picoline is used as a building block for the synthesis of pharmaceutical products. Its presence in such products can contribute to their biological activity or modify their physical and chemical properties, making it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
2-Chloro-4-Bromo-3-Picoline is used as a building block for the synthesis of agrochemical products. Its reactivity and ability to modify the properties of the final products make it a useful intermediate in the creation of effective agrochemicals.
Used in Coordination Chemistry:
2-Chloro-4-Bromo-3-Picoline is used as a ligand in coordination chemistry, forming complexes with metals. Its distinct structure allows it to participate in the formation of various metal complexes, which can have applications in different fields.
Used in Chemical Industry:
2-Chloro-4-Bromo-3-Picoline is used as a speciality chemical intermediate. Its reactivity and ability to form complex molecules make it a valuable component in the production of certain drugs or speciality chemicals.
However, due to its distinct structure, the safety and environmental implications of its use need to be considered carefully.

InChI:InChI=1/C6H5BrClN/c1-4-5(7)2-3-9-6(4)8/h2-3H,1H3

Upstream product

• 73583-37-6 2-chloro-4-bromopyridine 
• 74-88-4 methyl iodide 
• 52200-48-3 3-bromo-2-chloropyridine 

Downstream Products

• 1334589-72-8 3-(4-((2-chloro-3-methylpyridin-4-yl)ethynyl)phenyl)propanoic acid 
• 1334589-85-3 methyl 3-(4-((2-chloro-3-methylpyridin-4-yl)ethynyl)phenyl)-propanoate 

Relevant academic research and scientific papers

Pyrimidine or pyridine pyridine ketone compound and its preparation method and application (by machine translation)

The invention discloses a kind of type I of the pyrimidine or pyridine pyridine ketone compound and its preparation and application, which belongs to the technical field of pharmaceutical preparation. The compounds have high-efficient and selectively inhibit the cell cycle dependent kinases (Cdks) CDK4 and CDK6 active, and then by inhibiting CDK4/CDK6 prevent tumor cell division. Therefore, the compounds of this invention can be used for CDK4 and CDK6 the involved in cell cycle control disorders result in various diseases, especially suitable for the treatment of malignant tumors. (by machine translation)

Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties

The free fatty acid receptor 1 (FFA1, also known as GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and is recognized as an interesting new target for treatment of type 2 diabetes. Several series of selective FFA1 agonists are already known. Most of these are derived from free fatty acids (FFAs) or glitazones and are relatively lipophilic. Aiming for the development of potent, selective, and less lipophilic FFA1 agonists, the terminal phenyl of a known compound series was replaced by nitrogen containing heterocycles. This resulted in the identification of 37, a selective FFA1 agonist with potent activity on recombinant human FFA1 receptors and on the rat insulinoma cell line INS-1E, optimal lipophilicity, and excellent in vitro permeability and metabolic stability.

Migration du lithium en serie pyridinique: double catalyse et reformage. Acces aux derives de la bromo-2 lithio-3 pyridine et des bromo-4 halogeno-2 lithio-3 pyridines

The lithium of an organolithium-pyridinic derivative can be moved from one position to an another by an intermolecular reaction.Two new reactions are possible for pyridinic organic synthesis: the isomerisation of any lithio derivative to a more stable one, and a reaction that transforms a mixture of various bromo-lithio derivatives into a single one.The processes involved and the experimental tools used are described in terms of the 2-bromo-3-lithio- and 4-bromo-2-halogeno-3-lithiopyridines derivatives synthesis.