1280723-50-3Relevant academic research and scientific papers
Oxidative Cyclization of β-Aminoacrylamides Mediated by PhIO: Chemoselective Synthesis of Isoxazoles and 2 H-Azirines
Li, Chaoran,Yuan, Jingwen,Zhang, Qian,Bhujanga Rao, Chitturi,Zhang, Rui,Zhao, Yanning,Deng, Bicheng,Dong, Dewen
, p. 14999 - 15008 (2018/12/14)
Cyclization of a variety of β-aminoacrylamides in the presence of iodosobenzene (PhIO) is described. This process features mild reaction conditions, simple execution, and high chemoselectivity and thereby provides an efficient protocol for the divergent s
Vilsmeier reaction of 3-aminopropenamides: One-pot synthesis of pyrimidin-4(3 H)-ones
Zhang, Rui,Zhang, Dingyuan,Liang, Yongjiu,Zhou, Guangyuan,Dong, Dewen
supporting information; experimental part, p. 2880 - 2883 (2011/05/28)
A facile one-pot synthesis of pyrimidin-4(3H)-ones was developed via reactions of a series of readily available 3-aminopropenamides with varied Vilsmeier reagents, and a mechanism involving sequential halogenation, formylation, and intramolecular nucleoph
