1280737-87-2Relevant academic research and scientific papers
Highly regio-and stereoselective nickel-catalyzed addition of dialkyl phosphites to ynamides: An efficient synthesis of β-aminovinylphosphonates
Fadel, Antoine,Legrand, Frederic,Evano, Gwilherm,Rabasso, Nicolas
supporting information; experimental part, p. 263 - 267 (2011/04/16)
A highly regio-and stereoselective, nickel(II)-catalyzed procedure for the hydrophosphonylation of ynamides has been developed. This protocol provides a straightforward and efficient entry to a series of β-aminovinylphosphonates that can easily be prepared in good yields from a wide range of ynamides and dialkyl phosphites as well as useful insights into the reactivity of ynamides under nickel catalysis.
