1280786-75-5 Usage
General Description
5-Bromo-2-butyl-2H-indazole is a chemical compound classified as an indazole derivative. It is a white crystalline solid with the molecular formula C11H14BrN. 5-Bromo-2-butyl-2H-indazole is used in scientific research and pharmaceutical development as a building block in the synthesis of biologically active molecules. Its structure contains a bromine atom and a butyl group, which contribute to its chemical and physical properties. 5-Bromo-2-butyl-2H-indazole has potential applications in drug discovery and medicinal chemistry due to its ability to interact with biological targets and modulate physiological processes. Its unique structure and reactivity make it a valuable tool in the development of new therapeutic agents and research probes in various fields of science.
Check Digit Verification of cas no
The CAS Registry Mumber 1280786-75-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,0,7,8 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1280786-75:
(9*1)+(8*2)+(7*8)+(6*0)+(5*7)+(4*8)+(3*6)+(2*7)+(1*5)=185
185 % 10 = 5
So 1280786-75-5 is a valid CAS Registry Number.
1280786-75-5Relevant articles and documents
Regioselective synthesis of 2 H-indazoles using a mild, one-pot condensation-cadogan reductive cyclization
Genung, Nathan E.,Wei, Liuqing,Aspnes, Gary E.
, p. 3114 - 3117 (2014/06/23)
An operationally simple and efficient one-pot synthesis of 2H-indazoles from commercially available reagents is reported. Ortho-imino-nitrobenzene substrates, generated via condensation, undergo reductive cyclization promoted by tri-n-butylphosophine to afford substituted 2H-indazoles under mild reaction conditions. A variety of electronically diverse ortho-nitrobenzaldehydes and anilines were examined. To further extend the scope of the transformation, aliphatic amines were also employed to form N2-alkyl indazoles selectively under the optimized reaction conditions.
