128102-70-5

Upstream product

• 13734-41-3 t-Boc-L-valine 
• 76880-29-0 N-α-tert-butoxycarbonyl-S-(3-nitro-2-pyridylthio)-L-cysteine 

Relevant academic research and scientific papers

Potent Affinity Labeling Peptide Inhibitors of Calpain

We have employed a recently described affinity labeling approach using S-(3-nitro-2-pyridinesulfenyl) group (Npys) to devise unique inhibitors of the Ca++-dependent thiol protease, calpain.Compounds with Npys group bound on the peptides with Leu-Leu or Val-Val sequences were found to be highly potent inhibitors of calpain.