128109-28-4

Upstream product

• 824-94-2 p-methoxybenzyl chloride 
• 22639-17-4 2-hydroxymethyl-3-hydroxy-6-methyl-pyran-4(1H)-one 

Downstream Products

• 1151788-60-1 2-(biphenyl-4-ylmethoxymethyl)-3-(4-methoxy-benzyloxy)-6-methyl-pyran-4-one 
• 1151788-65-6 methanesulfonic acid 3-(4-methoxy-benzyloxy)-6-methyl-4-oxo-4H-pyran-2-ylmethyl ester 
• 439078-00-9 3-(4-Methoxy-benzyloxy)-6-methyl-2-[(E)-3-((R)-toluene-4-sulfinyl)-allylsulfanylmethyl]-pyran-4-one 
• 439078-01-0 3-(tert-Butyl-dimethyl-silanyloxy)-6-methyl-2-[(E)-3-((R)-toluene-4-sulfinyl)-allylsulfanylmethyl]-pyran-4-one 
• 439079-57-9 (1R,5R,6R,7R)-9-(tert-Butyl-dimethyl-silanyloxy)-7-methyl-6-((R)-toluene-4-sulfinyl)-11-oxa-3-thia-tricyclo[5.3.1.0^1,5]undec-8-en-10-one 
• 439077-99-3 2-bromomethyl-3-(4-methoxy-benzyloxy)-6-methyl-pyran-4-one 

Relevant academic research and scientific papers

Synthesis of hydroxypyrone- and hydroxythiopyrone-based matrix metalloproteinase inhibitors: Developing a structure-activity relationship

The zinc(II)-dependent matrix metalloproteinases (MMPs) are associated with a variety of diseases. Development of inhibitors to modulate MMP activity has been an active area of investigation for therapeutic development. Hydroxypyrones and hydroxythiopyron

A practical route to enantiopure, highly functionalized seven-membered carbocycles and tetrahydrofurans: Concise synthesis of (+)-nemorensic acid

Highly diastereoselective thermal [5C+2C] intramolecular pyrone-alkene cycloadditions can be achieved by introducing a homochiral p-tolylsulfinyl group at a suitable position of the alkene. The resulting adducts can be readily desulfinylated to give optic

Cephalosporin compounds and antibacterial agents

Novel cephalosporin compounds represented by formula (I): STR1 wherein R1 represents a lower alkyl group which may optionally have a substituent; each of R2 and R3 independently represents a hydrogen atom or hydroxy group; and A represents a hydrogen atom or a residue of nucleophilic compound, and pharmacologically acceptable salts or esters thereof exhibit a potent antibacterial activity against gram positive and gram negative bacteria.