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N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-D-histidyl-L-prolinamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

128111-65-9

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128111-65-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 128111-65-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,1,1 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 128111-65:
(8*1)+(7*2)+(6*8)+(5*1)+(4*1)+(3*1)+(2*6)+(1*5)=99
99 % 10 = 9
So 128111-65-9 is a valid CAS Registry Number.

128111-65-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (4S)-N-[(2R)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-1-methyl-2,6-dioxo-1,3-diazinane-4-carboxamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:128111-65-9 SDS

128111-65-9Downstream Products

128111-65-9Relevant academic research and scientific papers

Novel Process for Preparing Taltirelin and Its Intermediates

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Paragraph 0118-0126, (2020/09/30)

The present invention relates to a novel method for manufacturing taltirelin and an intermediate thereof. More specifically, the present invention discloses: a manufacturing method which uses a fluorenylmethoxycarbonyl (Fmoc)-trityl-histidine as a starting material, and manufactures taltirelin through a process of manufacturing histidyl-trityl-prolineamide, which is an intermediate of talthyreline by an in situ reaction, thereby being suitable for industrial mass production by manufacturing taltirelin in a high yield and high purity in a short time compared to existing technology; and a method for manufacturing histidyl-trityl-prolineamide for the same.

Novel Preparation for Taltirelin by Solid Phase Peptide Synthetic Method

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Paragraph 0054-0075, (2016/10/07)

PURPOSE: A novel method for preparing taltirelin by solid phase peptide synthesis is provided to quickly terminate compound synthesis and to obtain a final compound in high yield and purity. CONSTITUTION: A method for preparing taltirelin comprises: a step of preparing resin in which a Fmoc[9H-fluoren-9-ylmethoxycarbonyl]; protection group is removed; a step of coupling the Fmoc-proline with the resin; a step of removing the Fmoc protection group from the coupled proline; a step of coupling Fmoc-histidine to the proline; a step of removing the Fmoc protection group from the histidine; a step of coupling 1-methyl-4,5-dihydro orotic acid with the histidine; and a step of isolating peptides from the resin. The method further comprises a step of purifying the taltirelin; a step of converting the crystalline form of taltirelin into an alpha form; and a step of freeze-drying the taltirelin.

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